Oscar and Paul work at The Scar Free Foundation Programme of Wound Healing Research at the University of Bristol. Their work uses a unique research pipeline to speed up the process of finding and then testing possible scarring genes. By analysing huge gene databanks, Paul and the team are identifying genes that potentially influence how well - or poorly - we scar. Then, using gene-editing technology, they can tweak the same genes in zebrafish and measure the effect on wound healing.
The work being done by Oscar, Paul, and all the other talented researchers at our lab at the University of Bristol could be the key to scar free healing. If we can identify the genes that cause 'bad' scarring, we could screen patients in advance and offer bespoke treatments to those in danger of life-changing scarring.
Learn more about our research projects at the University of Bristol:
Integrating human and animal studies to investigate known clefting genes linked to wound healing
Using large cohort studies to identify genetic variants for mechanistic testing in mouse and zebrafish models of wound healing